• 中国计算机学会会刊
  • 中国科技核心期刊
  • 中文核心期刊

J4 ›› 2015, Vol. 37 ›› Issue (01): 7-13.

• 论文 • 上一篇    下一篇

计算生物学中的高性能计算(Ⅱ)—序列分析

王涛   

  1. (上海超级计算中心,上海 201203)
  • 收稿日期:2014-10-15 修回日期:2014-12-20 出版日期:2015-01-25 发布日期:2015-01-25

High performance computing in computational
biology (Ⅱ)—sequence analysis 

WANG Tao   

  1. (Shanghai Supercomputer Center,Shanghai 201203,China)
  • Received:2014-10-15 Revised:2014-12-20 Online:2015-01-25 Published:2015-01-25

摘要:

序列分析是高性能计算应用的一个重要方向。随着高通量测序技术的发展,基因数据呈现爆炸性增长,对高性能计算的需求也更加迫切。介绍了高性能计算在序列分析中的应用和序列分析算法的并行实现,包括序列比对、检索、重测序、拼接等。

关键词: 高性能计算应用, 计算生物学, 序列分析

Abstract:

Sequence analysis is an important domain of high performance computing applications.With the development of highthroughput sequencing technique,there is an explosive growth in genome data,and the demand for high performance computing becomes more urgent.The paper introduces the applications of high performance computing in sequence analysis and parallel implementation of sequence analysis algorithms, including sequence alignment,database search,resequencing, and genome assembly.

Key words: high performance computing application;computation biology sequence analysis