This paper focuses on how to improve students’ information literacy, computational thinking and computer design ability, in order to promote students’ scientific research innovation ability and to provide innovative power for sustainable development of scientific research. Additionally, taking the long-term and stable progressive development of equipment scientific research as a basic goal and relying on subject competition, computer grade examination and open MOOC laboratory platform, we can realize the exploration on training model of practical innovation ability for students at different levels. Through the optimization and reorganization of teaching contents, the transformation from scientific research achievements to teaching achievements can be realized, so that the teaching contents can be equipped with advanced technology and perspective thinking. In sum, the paper is beneficial to improve the students’ computer design ability, enhance the teaching effect of “university computer foundation” course, accelerate the students’ transformation from curriculum-based learning to the combination of curriculum-based learning and scientific research innovation ability, and motivate the students’ scientific research ability.